Lisa "Duffy" Duffin

Lisa Duffin - known to all as Duffy - joined the ED as a newly qualified nurse. She was carefree, with an interest in astrology, yo-yo diets, gossiping and trying to pass her driving test. But she was always shown to be a tough, determined woman, arranging a demonstration against the closure of the nightshift. However her happy go lucky character changed when she was raped. She didn't go to the police - which she later regretted - instead confiding in Megan. Duffy was promoted to Sister and fell pregnant by one of the doctors, Andrew. However, she realized she didn't love him and decided to raise the baby alone. Duffy did eventually marry Andrew and they decided to leave Holby when she became pregnant with her second child. Four years later Duffy and Andrew returned to Holby and Duffy came back to the ED as an agency nurse. She applied for the position of Sister and became permanent staff again. Duffy began an affair with one of her colleagues, Max, but ended it when Charlie pointed out that she could destroy her family. She became pregnant for a third time. Andrew was initially unsupportive but when Duffy nearly had a miscarriage Andrew decided to make things work - only to die after being pushed down the stairs by an irate patient. Later, Duffy fell in love with security guard Ryan but he betrayed her by stealing money from her savings account. Realizing the error of his ways, Ryan found a way to pay Duffy back and the pair were reconciled, leaving for a fresh start in New Zealand.