The Point of No Return

"The Point of No Return" is the 391st episode of Casualty and the 31st episode of the 17th series. It featured the departure of Lisa "Duffy" Duffin, portrayed by Cathy Shipton. However, Shipton returned as the character for guest appearances from 2006 onwards, the most recent being in 2016.

Synopsis
Jack tries to persuade a reluctant Tony to accept Eddie's offer of a kidney and Simon is shocked when Jane leaves hospital early, especially as she refuses to let him care for her. Duffy faces a life-changing decision following Ryan's return to Holby and Anna is devastated to learn the truth about Merlin. Meanwhile, Les Dennis makes a guest appearance as a bullying boss who drives an employee to suicide and finds his life in danger from her enraged husband.